Tadagra 40mg- As recommended by our customers as the best weekender
Tadagra are for the treatment of erectile dysfunction. This highly effective ED treatment contains the active ingredient tadalafil in a 40mg dose. Tadagra works the same as other ED Pills.. But has the benefits of lasting up 36 hours
Though Tadalafil 40mg sounds very similar to Tadalafil, it is different from it in its pharmaceutical formulation although it contains tadalafil in the generic form. Tadalafil super active is available under commercial names Tadagra, Tadalies.
Tadalafil 40mg is useful for treating erectile dysfunction in adult men. But, it cannot work without sexual stimulation.
Tadagra Mechanism of Action
Tadalafil 40mg (Tadagra) is a drug that works in improving the possibility of penile erection and also helpful in maintaining this erection during sexual intercourse in men suffering from erectile dysfunction. This medication targets a group of enzymes known as PDE5 and works by inhibiting its actions.
PDE5 is responsible to counter the actions of another enzyme called cGMP. The role of cGMP is to bind with proteins present in the smooth muscles of the penis and help in the relaxation of these smooth muscles. This also helps in increased blood flow to the penis.
On sexual stimulation, there is the release of nitric oxide and acetylcholine. These will work together with guanylate cyclase which then brings about the production of cGMP. As long as the level of cGMP is elevated, the smooth muscle relaxation of the penis continues and erection is maintained.
In normal cycles, once sexual arousal is over, the enzyme PDE5 causes breakdown of the cGMP thus bringing an end to the smooth muscle relaxation and reduction of blood flow to the penis. This brings about an end to the erection. Since Tadalafil Super Active targets and prevents the actions of PDE5, the level of cGMP remains elevated and the erection is maintained for a longer duration of time.
Tadalafil 40mg Indications for Use
Tadalafil 40mg is indicated for use in men suffering from erectile dysfunction. This medication is not indicated for use in women or in children. Only men over the age of 18 years are safe to use the drug.
Tadagra 40mg is not indicated for use in men who enjoy a healthy erection. This is important as the intake of this medication in healthy men can induce permanent and irreparable damage to the penis.
Tadalafil 40mg (tadagra) contraindications
Tadalafil Super Active is contraindicated for use in men who are suffering from other medical problems. Some of the conditions in which the drug should not be used include:
- Known allergy to any constituents of Tadalafil (tadagra)
- If the person is on drugs such as nitrates, (nitrogen oxide) NO donor or protease inhibitors.
- Persons suffering from heart aliments such as severe hypertension, angina, severe hypotension, heart rhythm abnormalities, angina, coronary artery disease, stroke or heart attacks should not use Tadagra due to the risk of complications.
- It is not recommended to use Tadalafil if the person is suffering from blood related conditions such as leukemia, anemia or multiple myeloma.
- People suffering from severe kidney problems and liver conditions should not use Tadalafil.
- It is not advisable for women to take Tadagra 40mg as its safety and effects have not been studied in them.
- It is not advisable for anyone below 18 years to use the drug as the effects and safety has not been established through clinical trials.
Special Precautions (tadagra)
Special precaution should be used prior to taking Tadalafil 40mg in people with heart conditions. In such conditions, it is best to first consult with the cardiologist before starting on the medication.
If the person is suffering from any kind of liver or kidney diseases, proper assessment and advice from a qualified doctor should be taken to check if it is safe to take Tadagra 40mg.
People suffering from diabetes should seek suitable advice and assessment from their doctor to check for any other predisposing conditions that might make it unsafe for them to take Tadagra 40mg.
If the person has penile deformities, then Tadagra 40mg may not be recommended. If the person has priapism (prolonged erection) or any conditions that carry the risk of priapism such as leukemia, multiple myeloma, sickle cell anemia or thrombocythemia, then the use of the medication should be with caution, proper assessment and advice from a qualified doctor.
Tadalafil (Tadagra 40mg) Drug Interactions
Some drugs cause drug interactions when taken along with Tadalafil 40mg. So, if a person is taking any of the below mentioned medications, then the use of Tadagra 40mg should be avoided or taken only after proper consultation and assessment from a qualified doctor. Some of the medications that can cause drug interactions with Tadalafil 40mg include:
- Nitrates – these might induce the reduction of blood pressure.
- Anti-arrhythmic drugs – these might cause abnormalities of rhythm.
- Macrolide antibiotics and protease inhibitors – these raise blood levels of Tadagra 40mg.
- Alpha-blockers – these have the tendency to cause side effects like feeling faint, dizzy or lightheaded.
- Antifungal medications – these have the tendency to cause more adverse effects from Tadagra 40mg.
Mode of Administration
Tadalafil 40mg (Tadagra) should not be taken without prior consultation from a doctor who is qualified to prescribe the medication. The medication is manufactured in the form of gelatin capsules and is available in strengths of 20 mg.
While taking the medication, one should remember that the whole capsule should be swallowed without crushing it or chewing on it. It should be followed with adequate amount of water to enable its easy absorption.
Tadagra 40mg needs about 30 minutes for it to initiate its effects. The effects usually last for duration of about 36 hours. To avoid overdose and serious complications, it is advisable not to exceed the dose of 40mg in a day.
Tadagra Adverse Effects
In most of the people, Tadagra 40mg will not show any serious side effects. Most of the adverse effects seen will be of mild to moderate nature. The most common of side effects seen will be headache, muscular pain, hot flashes, myalgia, blurring of the vision, dyspepsia, and nasal congestion. However, if a person experiences these side effects, they will not need any kind of intervention nor will they need to stop the intake of Tadalafil 40mg.
In some cases, rare side effects such as vertigo, dryness of the mouth, rashes, insomnia, vision or hearing difficulties, severe increase in blood pressure, hives pain during erection and prolonged erection can be seen.
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